SPIRO-CLEAR II

Spiro-Clear ll

SPIRO-CLEAR II is an elite core immune support herbal formula for people with Lyme disease and other immune presentations.

Ingredients: 100gm Container – Bulk Herb Extract 10:1

• Scutellaria
• Phellodendron
• Pulsitilla
• Korean Ash Bark
• Clove
• Forsythia
• Gardenia
• Zedoria Curcuma
• Lumbricus
• Teasle
• Red Sage Root
• Cassia

Formulated by Chinese Medicine Herbalist

* Do not take during pregnancy

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Research: Other research citations not included for some herbs on Spiro-Clear I

• Łaska G, Sienkiewicz A. Antifungal activity of the rhizome extracts of Pulsatilla vulgaris against Candida glabrata. European Journal of Biological Research. 2019;9(2):93-103. doi:10.5281/zenodo.3228890.
• Song J-H, Park K, Shim A, et al. Complete sequence analysis and antiviral screening of medicinal plants for human coxsackievirus a16 isolated in Korea. Osong Public Health And Research Perspectives. 2015;6(1):52-58. doi:10.1016/j.phrp.2014.12.004.
• Youn HJ, Lakritz J, Kim DY, Rottinghaus GE, Marsh AE. Anti-protozoal efficacy of medicinal herb extracts against Toxoplasma gondii and Neospora caninum. Veterinary Parasitology. 2003;116(1):7. doi:10.1016/S0304-4017(03)00154-7.
• https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulsatilla
• Ma X, Liu X, Feng J, et al. Fraxin Alleviates LPS-Induced ARDS by Downregulating Inflammatory Responses and Oxidative Damages and Reducing Pulmonary Vascular Permeability. Inflammation. 2019;42(5):1901-1912. doi:10.1007/s10753-019-01052-8.
• Wu B, Wang R, Li S, et al. Antifibrotic effects of Fraxetin on carbon tetrachloride-induced liver fibrosis by targeting NF-κB/IκBα, MAPKs and Bcl-2/Bax pathways. Pharmacological Reports: PR. 2019;71(3):409-416. doi:10.1016/j.pharep.2019.01.008.
• Irshad S, Muazzam A, Shahid Z, Dalrymple MB. Curcuma longa (Turmeric): An auspicious spice for antibacterial, phytochemical and antioxidant activities. Pakistan Journal Of Pharmaceutical Sciences. 2018;31(6 (Supplementary):2689-2696.
• Tungcharoen P, Wattanapiromsakul C, Tansakul P, Nakamura S, Matsuda H, Tewtrakul S. Antiinflammation constituents from Curcuma zedoaroides. Phytotherapy Research: PTR. 2018;32(11):2312-2320. doi:10.1002/ptr.6173.
• Mustaqim Othman AF, Rukayadi Y, Radu S. Inhibition of Pseudomonas aeruginosa Quorum Sensing by Curcuma xanthorrhiza Roxb. Extract. Journal of Pure & Applied Microbiology. 2019;13(3):1335-1347. doi:10.22207/JPAM.13.3.05.
• Kukula-Koch W, Grabarska A, Łuszczki J, et al. Superior anticancer activity is demonstrated by total extract of Curcuma longa L. as opposed to individual curcuminoids separated by centrifugal partition chromatography. Phytotherapy Research: PTR. 2018;32(5):933-942. doi:10.1002/ptr.6035.
• Grover M, Shah K, Khullar G, Gupta J, Behl T. Investigation of the utility of Curcuma caesia in the treatment of diabetic neuropathy. The Journal Of Pharmacy And Pharmacology. 2019;71(5):725-732. doi:10.1111/jphp.13075.
• Jang H-J, Park E-J, Lee S-J, et al. Diarylheptanoids from Curcuma phaeocaulis Suppress IL-6-Induced STAT3 Activation. Planta Medica. 2019;85(2):94-102. doi:10.1055/a-0668-0962.
• Liu Y, Liu F, Qiao M-M, et al. Curcumanes A and B, Two Bicyclic Sesquiterpenoids with Significant Vasorelaxant Activity from Curcuma longa. Organic Letters. 2019;21(4):1197-1201. doi:10.1021/acs.orglett.9b00149.
• Han H, Wang L, Liu Y, et al. Combination of curcuma zedoary and kelp inhibits growth and metastasis of liver cancer in vivo and in vitro via reducing endogenous H2S levels. Food & Function. 2019;10(1):224-234. doi:10.1039/c8fo01594e.
• Li KK, Zhou X, Wong HL, et al. In vivo and in vitro anti-inflammatory effects of Zao-Jiao-Ci (the spine of Gleditsia sinensis Lam.) aqueous extract and its mechanisms of action. Journal Of Ethnopharmacology. 2016;192:192-200. doi:10.1016/j.jep.2016.07.020.
• Gao J, Yang X, Yin W. From Traditional Usage to Pharmacological Evidence: A Systematic Mini-Review of Spina Gleditsiae. Evidence-based Complementary & Alternative Medicine (eCAM). 2016;2016:1-6. doi:10.1155/2016/3898957.
• Arbiser JL, Fisher DE. Fisetin: A Natural Fist against Melanoma? Journal of Investigative Dermatology. 2011;131(6):1187-1189. doi:10.1038/jid.2011.39.
• Arbiser JL, Fisher DE. Fisetin: A Natural Fist against Melanoma? Journal of Investigative Dermatology. 2011;131(6):1187-1189. doi:10.1038/jid.2011.39.